Detalhe da pesquisa
1.
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.
Nature
; 595(7865): 107-113, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33915569
2.
A scalable approach to characterize pleiotropy across thousands of human diseases and complex traits using GWAS summary statistics.
Am J Hum Genet
; 110(11): 1863-1874, 2023 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37879338
3.
Partitioning gene-mediated disease heritability without eQTLs.
Am J Hum Genet
; 109(3): 405-416, 2022 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35143757
4.
Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes.
Am J Hum Genet
; 109(4): 692-709, 2022 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35271803
5.
An integrated approach to identify environmental modulators of genetic risk factors for complex traits.
Am J Hum Genet
; 108(10): 1866-1879, 2021 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34582792
6.
Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations.
Hum Mol Genet
; 30(16): 1521-1534, 2021 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33987664
7.
Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability.
Hum Mol Genet
; 29(7): 1057-1067, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31595288
8.
Disease Heritability Enrichment of Regulatory Elements Is Concentrated in Elements with Ancient Sequence Age and Conserved Function across Species.
Am J Hum Genet
; 104(4): 611-624, 2019 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30905396
9.
Extreme Polygenicity of Complex Traits Is Explained by Negative Selection.
Am J Hum Genet
; 105(3): 456-476, 2019 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31402091
10.
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
Am J Hum Genet
; 104(1): 65-75, 2019 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30595370
11.
IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors.
Am J Hum Genet
; 104(5): 879-895, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31006511
12.
Genes with High Network Connectivity Are Enriched for Disease Heritability.
Am J Hum Genet
; 104(5): 896-913, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31051114
13.
MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease.
N Engl J Med
; 379(23): 2209-2219, 2018 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30345907
14.
Methotrexate and rheumatoid arthritis associated interstitial lung disease.
Eur Respir J
; 57(2)2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32646919
15.
Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank.
J Allergy Clin Immunol
; 145(2): 537-549, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31669095
16.
Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues.
Am J Hum Genet
; 100(4): 605-616, 2017 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28343628
17.
Truncating mutations of TP53AIP1 gene predispose to cutaneous melanoma.
Genes Chromosomes Cancer
; 57(6): 294-303, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29359367
18.
Genes with High Network Connectivity Are Enriched for Disease Heritability.
Am J Hum Genet
; 105(6): 1302, 2019 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31809749
19.
Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis.
Eur Respir J
; 49(5)2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28495692
20.
Relationship inference from the genetic data on parents or offspring: A comparative study.
Theor Popul Biol
; 107: 31-8, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26431644